Time-Varying Light Exposure in Chronobiology and Sleep Research Experiments

Light exposure profoundly affects human physiology and behavior through circadian and neuroendocrine photoreception primarily through the melanopsin-containing intrinsically photosensitive retinal ganglion cells.Recent research slippers has explored the possibility of using temporally patterned stimuli to manipulate circadian and neuroendocrine responses to light.This mini-review, geared to chronobiologists, sleep researchers, and scientists in adjacent disciplines, has two objectives: (1) introduce basic concepts in time-varying NosiLife Socks stimuli and (2) provide a checklist-based set of recommendations for documenting time-varying light exposures based on current best practices and standards.